Monday, November 12, 2007

Mutant gene behind cancer identified

LONDON:
Scientists at University College London’s Prostate Gland Cancer Research Centre
have identified a mutant factor that assists distribute prostate gland malignant neoplastic disease through the
body. The research workers believe
that their discovery survey will pave the manner for drugs which mark the
mutation and halt the cancer
spreading. "We have got identified
mutations in a factor that assists to command cell movement. We believe that the
cancer cells have got hijacked this factor to assist them spread,” said Dr Magali
Williamson, who led the squad at the Prostate Gland Cancer Research Centre at
University College London. "We
found mutants in nearly half of the malignant neoplastic diseases restricted to the prostate, and
nearly all the 1s that have got spread, suggesting that the mutants might be
helping the malignant neoplastic disease cells spread," he
added. During the study, the
researchers examined 12 prostate gland malignant neoplastic disease patients whose disease had spread, and
found that 90 percentage of them had the mutant
gene. They also looked at 100
men whose malignant neoplastic disease had not spread, and observed that lone 45 percentage of them had
the mutant gene. They have got also
found that work force who were fleshy when diagnosed with prostate gland malignant neoplastic disease were
twice more than likely to decease from the
disease. Professor John
Masters, a specializer at the centre, said: "If we could switch over off this gene
with drugs we might forestall its spreading and salvage lives.”

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